Raffaella Cioffi

Biography

Dr. Raffaella Cioffi is a Gynecologist at the Obstetrics and Gynecology Unit of IRCCS Ospedale San Raffaele in Milan, directed by Professor Massimo Candiani.

After graduating with honors and distinction in Medicine and Surgery from Università Vita-Salute San Raffaele in 2014, she specialized in Gynecology and Obstetrics at the same university in 2020. From 2019 to 2022, she pursued a PhD in Molecular Medicine (Clinical and Experimental Medicine Curriculum) at Università Vita-Salute San Raffaele, focusing on fertility preservation in cancer patients.

Clinically, Dr. Cioffi primarily focuses on medical and surgical gynecological oncology, with a particular interest in diagnosing and treating rare tumors of the female genital tract and in fertility preservation techniques for cancer patients. She also performs regular gynecological ultrasound diagnostics and provides on-call services in the delivery room and obstetric/gynecological emergency care.

Dr. Cioffi is involved in clinical research as a co-investigator in national and international phase II and III clinical trials exploring innovative treatments for gynecological cancers.

She is a member of several scientific societies, including the European Society of Gynecological Oncology (ESGO), the Multicenter Italian Trials in Ovarian Cancer and Gynecologic Malignancies (MITO), and the European Organization for the Treatment of Trophoblastic Disease (EOTTD). Additionally, she has authored and co-authored numerous articles in international scientific journals and regularly participates in national and international conferences in her field.

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Publications

Latest publications

A prospective, observational study of chemotherapy-induced ovarian damage on follicular reserve and maturation
Arch Gynecol Obstet. 2022 Nov;306(5):1723-1729.
Cioffi R, Cervini L, Taccagni G, Papaleo E, Pagliardini L, Bergamini A, Ferrari S, Mangili G, Candiani M.
OReO/ENGOT Ov-38 trial: Impact of maintenance olaparib rechallenge according to ovarian cancer patient prognosis—An exploratory joint analysis of the BRCA and non-BRCA cohorts
DOI:10.1200/JCO.2022.40.16_suppl.5558 Journal of Clinical Oncology 40, no. 16_suppl (June 01, 2022) 5558-5558.
Frederic Selle, Bernard Asselain, François Montestruc, Fernando Bazan, Beatriz Pardo, Vanda Salutari, Frederik Marmé, Anja Ør Knudsen, Alessandra Bologna, Radoslaw Madry, Rosalind Glasspool, Stéphanie Henry, Jacob Korach, Stephanie Lheureux, Bob Shaw, Ana Santaballa, Raffaella Cioffi, Ulrich Canzler, Alain Lortholary, Eric Pujade-Lauraine.
Current Evidence on Immunotherapy for Gestational Trophoblastic Neoplasia (GTN)
Cancers (Basel). 2022 Jun 3;14(11):2782.
Mangili G, Sabetta G, Cioffi R, Rabaiotti E, Candotti G, Pella F, Candiani M, Bergamini A.
Ovarian failure risk in post-pubertal patients with cancer: a prognostic model
Future Oncol. 2022 Jun;18(19):2391-2400.
Cioffi R, Fais ML, Bergamini A, Vanni VS, Pagliardini L, Papaleo E, Mangili G, Candiani M.
Fertility sparing surgery in sex-cord stromal tumors: oncological and reproductive outcomes
Int J Gynecol Cancer. 2022 Apr 18:ijgc-2021-003241.
Bergamini A, Luisa FM, Dellino M, Erica S, Loizzi V, Bocciolone L, Rabaiotti E, Cioffi R, Sabetta G, Cormio G, Mangili G.
The neglected members of the family: non-BRCA mutations in the Fanconi anemia/BRCA pathway and reproduction
Hum Reprod Update. 2022 Feb 28;28(2):296-311.
Vanni VS, Campo G, Cioffi R, Papaleo E, Salonia A, Viganò P, Lambertini M, Candiani M, Meirow D, Orvieto R.
Do stage and grade of malignancy impact fertility preservation in breast cancer patients?
J Gynecol Obstet Hum Reprod. 2021 Dec;50(10):102215.
Cioffi R, Mangili G, Sarais V, Cervini L, Longo V, Bergamini A, Stella Vanni V, Pagliardini L, Candiani M, Papaleo E.
Impact of COVID-19 on medical treatment patterns in gynecologic oncology: a MITO group survey
Int J Gynecol Cancer. 2021 Oct;31(10):1363-1368.
Cioffi R, Sabetta G, Rabaiotti E, Bergamini A, Bocciolone L, Candotti G, Candiani M, Valabrega G, Mangili G, Pignata S; MITO group.
Inflammatory indexes as predictive factors for platinum sensitivity and as prognostic factors in recurrent epithelial ovarian cancer patients: a MITO24 retrospective study
Sci Rep. 2020 Oct 23;10(1):18190.
Farolfi A, Scarpi E, Greco F, Bergamini A, Longo L, Pignata S, Casanova C, Cormio G, Bologna A, Orditura M, Zavallone L, Attademo L, Gallà V, Franzese E, Pigozzi E, Loizzi V, Giorda G, Giardina D, Cioffi R, De Giorgi U.
Practical clinical guidelines of the EOTTD for treatment and referral of gestational trophoblastic disease
Eur J Cancer. 2020 May;130:228-240.
Lok C, van Trommel N, Massuger L, Golfier F, Seckl M; Clinical Working Party of the EOTTD.
What women want: Fertility sparing surgery in Borderline ovarian tumours patients and pregnancy outcome
Eur J Surg Oncol. 2019 Nov 3. pii: S0748-7983(19)30924-2.
Candotti G, Peiretti M, Mangili G, Bergamini A, Candiani M, Cioffi R, Mais V, Rabaiotti E, Bocciolone L.
A Pictorial Ultrasound Essay of Gestational Trophoblastic Disease
J Ultrasound Med. 2019 Aug 29
Cavoretto P, Cioffi R, Mangili G, Petrone M, Bergamini A, Rabaiotti E, Valsecchi L, Candiani M, Seckl MJ.
Does methotrexate (MTX) dosing in a 8-day MTX/FA regimen for the treatment of low-risk gestational trophoblastic neoplasia affect outcomes?
Gynecol Oncol 2018.
The MITO-9 study.” Mangili G, Cioffi R, Danese S, Frigerio L, Ferrandina G, Cormio G, Rabaiotti E, Scarfone G, Gadducci A, Bergamini A, Pisano C, Candiani M.
Neoadjuvant chemotherapy in high-risk ovarian cancer patients: role of age
Tumori. 2018 Aug 29:300891618792468.
Cioffi R, Bergamini A, Rabaiotti E, Petrone M, Pella F, Ferrari D, Mangili G, Candiani M.
Inflammatory Indexes as Prognostic and Predictive Factors in Ovarian Cancer Treated with Chemotherapy Alone or Together with Bevacizumab. A Multicenter, Retrospective Analysis by the MITO Group (MITO 24).
Target Oncol. 2018 Jun 14.
Farolfi A, Petrone M, Scarpi E, Gallà V, Greco F, Casanova C, Longo L, Cormio G, Orditura M, Bologna A, Zavallone L, Ventriglia J, Franzese E, Loizzi V, Giardina D, Pigozzi E, Cioffi R, Pignata S, Giorda G, De Giorgi U.
Reproductive Outcomes After Gestational Trophoblastic Neoplasia. A Comparison Between Single-Agent and Multiagent Chemotherapy: Retrospective Analysis From the MITO-9 Group.
Int J Gynecol Cancer. 2018 Jan 12.
Cioffi R, Bergamini A, Gadducci A, Cormio G, Giorgione V, Petrone M, Rabaiotti E, Pella F, Candiani M, Mangili G.

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