Maddalena Smid

السيرة الذاتية

Dr. Maddalena Smid is a gynecologist at the Gynecology and Obstetrics Unit of IRCCS Ospedale San Raffaele.  

She graduated with honors in Medicine and Surgery from the University of Milan in 1987, where she also specialized with honors in Gynecology and Obstetrics in 1991.  

Dr. Smid has an international background, having attended the German School of Milan and spending a year in London. There, she completed an internship at the prenatal diagnosis center of Queen Charlotte’s Hospital and later worked as a senior house officer in the obstetrics department of Hammersmith Hospital.  

She is a certified trainer for the UNICEF-WHO 20-hour course on breastfeeding and infant nutrition, designed for healthcare professionals caring for mothers and newborns.  

In 2019, she undertook specialized training on the "language of care" (ISTUD Foundation) to enhance communication skills with patients and among healthcare professionals.  

Dr. Smid is currently the head of the Obstetrics Department (high-risk pregnancy and postpartum care) and the pregnancy pathology outpatient clinics.  

She is an expert in maternal-fetal medicine, providing clinical and ultrasound monitoring of high-risk pregnancies, particularly those complicated by hypertension, fetal growth restriction, and placental disorders. She also serves as a lead physician in the delivery room and performs obstetric and gynecological ultrasounds.  

As the reference gynecologist for the UNICEF program that led to San Raffaele’s certification as a Baby-Friendly Hospital, she has developed a strong focus on the emotional and relational aspects of the mother-baby bond.  

In her outpatient practice, she follows both low- and high-risk pregnancies and provides care to women throughout different life stages, from adolescence to menopause.  

Dr. Smid is also actively involved in teaching and mentoring at the School of Medicine and Surgery and the Gynecology and Obstetrics Residency Program at Vita-Salute San Raffaele University. Her research focuses particularly on fetal DNA/RNA in maternal blood for identifying predictive markers of preeclampsia.

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المنشورات

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Early increase in circulating carbonic anhydrase IX: A potential new predictive biomarker of preeclampsia
Front Mol Biosci. 2023 Jan 19;10:1075604. doi: 10.3389/fmolb.2023.1075604. eCollection 2023. PMID: 36743209
Galbiati S, Gabellini D, Ambrosi A, Soriani N, Pasi F, Locatelli M, Lucianò R, Candiani M, Valsecchi L, Zerbini G, Smid M.
Renal dysfunction and podocyturia in pre-eclampsia may be explained by increased urinary VEGF
Nephrol Dial Transplant. 2022 May 25;37(6):1109-1117. doi: 10.1093/ndt/gfab175. PMID: 33950200
Valsecchi L, Galdini A, Gabellini D, Dell'Antonio G, Galbiati S, Fanecco A, Viganò I, Smid M, Bernardi R, Maestroni S, Baelde HJ, Zerbini G.
Mode of birth in women with low-lying placenta: protocol for a prospective multicentre 1:3 matched case-control study in Italy (the MODEL-PLACENTA study)
BMJ Open. 2021 Dec 6;11(12):e052510. doi: 10.1136/bmjopen-2021-052510. PMID: 34873004
Ornaghi S, Colciago E, Vaglio Tessitore I, Abbamondi A, Antolini L, Locatelli A,... Smid M,... Vergani P.
Prospective evaluation of RASSF1A cell-free DNA as a biomarker of pre-eclampsia (2015)
Placenta, 36 (9), pp. 996-1001.
Salvianti, F., Inversetti, A., Smid, M., Valsecchi, L., Candiani, M., Pazzagli, M., Cremonesi, L., Ferrari, M., Pinzani, P., Galbiati, S.
Evaluation of a panel of circulating DNA, RNA and protein potential markers for pathologies of pregnancy
Clin Chem Lab Med. 2010 Jun;48(6):791-4. doi: 10.1515/CCLM.2010.160. PMID: 20374043.
Galbiati S, Causarano V, Pinzani P, Francesca S, Orlando C, Smid M, Pasi F, Castiglioni MT, Cavoretto P, Rovere-Querini P, Pedroni S, Calza S, Ferrari M, Cremonesi L.
Correlation of fetal DNA levels in maternal plasma with Doppler status in pathological pregnancies
Prenat Diagn. 2006 Sep;26(9):785-90. doi: 10.1002/pd.1504. PMID: 16832835.
Smid M, Galbiati S, Lojacono A, Valsecchi L, Platto C, Cavoretto P, Calza S, Ferrari A, Ferrari M, Cremonesi L.
Fetal DNA detection in maternal plasma throughout gestation
Hum Genet. 2005 Jul;117(2-3):243-8. doi: 10.1007/s00439-005-1330-z. Epub 2005 May 20. PMID: 15906093.
Galbiati S, Smid M, Gambini D, Ferrari A, Restagno G, Viora E, Campogrande M, Bastonero S, Pagliano M, Calza S, Ferrari M, Cremonesi L.
No evidence of fetal DNA persistence in maternal plasma after pregnancy
Hum Genet. 2003 May;112(5-6):617-8. doi: 10.1007/s00439-003-0919-3. Epub 2003 Feb 27. PMID: 12607116.
Smid M, Galbiati S, Vassallo A, Gambini D, Ferrari A, Viora E, Pagliano M, Restagno G, Ferrari M, Cremonesi L.
Multiple testing in fetal gender determination from maternal blood by polymerase chain reaction
Hum Genet. 1998 Jun;102(6):687-90. doi: 10.1007/s004390050762. PMID: 9703431.
Lagona F, Smid M, Papasergio N, Ferrari A, Ferrari M, Cremonesi L.
Influence of gestational age on fetal deoxyribonucleic acid retrieval in maternal peripheral blood. Am J Obstet Gynecol
1997 Dec;177(6):1517-22. doi: 10.1016/s0002-9378(97)70101-7. PMID: 9423761.
Smid M, Lagona F, Papasergio N, Ferrari A, Ferrari M, Cremonesi L.

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