Alberto Andrea Zambon

职业:
神经科医生
语言:
EN
IT

个人简介

Dr. Alberto Andrea Zambon is a neurologist and pediatric neurologist consultant at the Neurology Unit of IRCCS Ospedale San Raffaele.

He graduated in Medicine and Surgery from Università Vita-Salute San Raffaele in 2013 and specialized in Neurology there in 2019. Following his specialization, he pursued a PhD in Molecular Medicine, focusing on Duchenne muscular dystrophy, from 2020 to 2023.

During his specialization (2018-2019) and as a research fellow (2020-2021), he spent two years at the Dubowitz Neuromuscular Centre at University College London, where he worked with pediatric patients with neuromuscular diseases at Great Ormond Street Hospital. In 2024, he completed an international master's program at the University of Milan on peripheral nervous system diseases.

Dr. Zambon provides consultations in the Neonatology and Pediatrics departments, led by Dr. Graziano Barera, and supports the Pediatric Immunohematology department directed by Professor Alessandro Aiuti.

His clinical work focuses on diagnosing and treating neurological diseases in children, with particular interest in neonatal neurology, follow-up of premature infants, and pediatric and adult neuromuscular diseases.

His research is primarily centered on hereditary neuromuscular diseases such as myopathies (e.g., dystrophinopathies, congenital muscular dystrophies like LAMA2-RD) and hereditary neuropathies. He is also involved in the study of patients with metachromatic leukodystrophy and has authored over 20 scientific publications.

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出版物

最新出版物

Early onset hereditary neuronopathies: an update on non-5q motor neuron diseases. Brain
2022 Nov 29:awac452. doi: 10.1093/brain/awac452. PMID: 36445400
Zambon AA, Pini V, Bosco L, Falzone YM, Munot P, Muntoni F, Previtali SC.
Molecular mechanisms and therapeutic strategies for neuromuscular diseases
Cell Mol Life Sci. 2024;81(1):308. Published 2024 Jul 26. doi:10.1007/s00018-02405305-0
Zambon AA, Falzone YM, Bolino A, Previtali SC.
Respiratory Function and Sleep Disordered Breathing in Pediatric Duchenne Muscular Dystrophy
Neurology. 2022;10.1212/WNL.0000000000200932. doi:10.1212/WNL.0000000000200932
Zambon AA, Trucco F, Laverty A, et al.
Definition of diaphragmatic sleep disordered breathing and clinical meaning in Duchenne muscular dystrophy
Thorax. 2024;79(7):652-661. Published 2024 Jun 14. doi:10.1136/thorax-2023-220729
Trucco F, Davies M, Zambon AA, Ridout D, Abel F, Muntoni F.
Peak functional ability and age at loss of ambulation in Duchenne muscular dystrophy
Dev Med Child Neurol. 2022;64(8):979-988. doi:10.1111/dmcn.15176
Zambon AA, Ayyar Gupta V, Ridout D, et al.
Phenotypic Spectrum of Dystrophinopathy Due to Duchenne Muscular Dystrophy Exon 2 Duplications. Neurology
2021;10.1212/WNL.0000000000013246. doi:10.1212/WNL.0000000000013246
Zambon AA, Waldrop MA, Alles R, et al.
Congenital muscular dystrophies: What is new?
Neuromuscul Disord. 2021;31(10):931-942. doi:10.1016/j.nmd.2021.07.009
Zambon AA, Muntoni F.
LAMA2-related muscular dystrophy: Natural history of a large pediatric cohort.z
Ann Clin Transl Neurol. 2020 Oct;7(10):1870-1882. doi: 10.1002/acn3.51172. Epub 2020 Sep 10. PMID: 32910545
Zambon AA, Ridout D, Main M, Mein R, Phadke R, Muntoni F, Sarkozy A.
Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients
J Inherit Metab Dis. 2021;1–14
Fumagalli F, Zambon AA*, Rancoita PMV, et al.
扩展阅读
Lentiviral haematopoietic stem-cell gene therapy for early-onset metachromatic leukodystrophy: long-term results from a non-randomised, open-label, phase 1/2 trial and expanded access
Lancet. 2022 Jan 22;399(10322):372-383. doi: 10.1016/S0140-6736(21)02017-1. PMID: 35065785; PMCID: PMC8795071.
Fumagalli F, Calbi V, Natali Sora MG, Sessa M, Baldoli C, Rancoita PMV, Ciotti F, Sarzana M, Fraschini M, Zambon AA, Acquati S, Redaelli D, Attanasio V, Miglietta S, De Mattia F, Barzaghi F, Ferrua F, Migliavacca M, Tucci F, Gallo V, Del Carro U, Canale S, Spiga I, Lorioli L, Recupero S, Fratini ES, Morena F, Silvani P, Calvi MR, Facchini M, Locatelli S, Corti A, Zancan S, Antonioli G, Farinelli G, Gabaldo M, Garcia-Segovia J, Schwab LC, Downey GF, Filippi M, Cicalese MP, Martino S, Di Serio C, Ciceri F, Bernardo ME, Naldini L, Biffi A, Aiuti A.

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