Matteo Maria Bellone

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Profession:

Immunologist

Location:

Department of Allergy, Immunology, Rheumatology and Rare Diseases @ Ospedale San Raffaele

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Biography

Dr. Matteo Bellone is an immunologist at the Clinical Unit of Immunology, Rheumatology, Allergology, and Rare Diseases at the IRCCS San Raffaele Hospital in Milan, directed by Professor Lorenzo Dagna.

In the field of Immunology and Immunopathology, he has been a subject matter expert at the University of Milan and is a contract professor at the Vita-Salute San Raffaele University since its foundation.

After graduating with honors in Medicine and Surgery from the University of Milan in 1986, Dr. Bellone spent three years at the University of Minnesota (USA). He then specialized with honors in Allergology and Clinical Immunology at the University of Milan in 1989.

Dr. Bellone’s clinical work focuses on the diagnosis and treatment of immune-mediated diseases, with a particular interest in sarcoidosis. He is actively involved in clinical research at the unit led by Professor Dagna.

He also heads the Cellular Immunology Unit at San Raffaele Hospital. His research interests have centered on the pathogenic mechanisms in autoimmunity and immune response to tumors, viewing these as two sides of the same coin. His studies have clarified certain mechanisms underlying immune responses in diabetes and myasthenia gravis, as well as in cancer. Furthermore, his research has led to the identification of new immunotherapeutic approaches, successfully tested in cancer patients.

Dr. Bellone is the author of over 120 scientific publications indexed by PubMed, as well as a book and several book chapters.

He serves as Associate Editor for Frontiers in Immunology and Oncology and reviews manuscripts and funding requests for national and international agencies and journals.

He has been Secretary and Treasurer of the Italian Network for Cancer Biotherapy (NIBIT), of which he remains a member. He is also on the Board of Directors of the European Network for Cancer Immunotherapy (ENCI), and is a member of the Italian Society of Immunology, Clinical Immunology and Allergology (SIICA), and the American Association for Cancer Research (AACR).

Education

University of Milan
Degree in Medicine and Surgery - 1986

University of Milan
Specialization in Allergology and Clinical Immunology - 1989

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Publications

Latest publications

Microbiota-propelled T helper 17 cells in inflammatory diseases and cancer.

Microbiol Mol Biol Rev. 2020 Mar 4;84(2):e00064-19. doi: 10.1128/MMBR.00064-19.

Bellone M, Calcinotto A, Huber S.

Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression.

Nat Commun. 2018 Dec 3;9(1):4832. doi: 10.1038/s41467-018-07305-8.

Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, Kumar S, Garbitt VM, Sharik ME, Henderson KJ, Tonon G, Tomura M, Miwa Y, Esplugues E, Flavell RA, Huber S, Canducci F, Rajkumar VS, Bergsagel PL, Bellone M.

Autoimmune Disease: Pathogenesis.

(September 2015) In: eLS. John Wiley & Sons, Ltd: Chichester. http://www.els.net/ DOI: 10.1002/9780470015902.

Bellone M.

A pilot phase I study combining peptide-based vaccination and NGR-hTNF vessel targeting therapy in metastatic melanoma.

Oncoimmunology 2014 Dec 21;3(11):e963406

Parmiani G, Pilla L, Corti A, Doglioni C, Cimminiello C, Bellone M, Parolini D, Russo V, Capocefalo F, Maccalli C.

Cellular microchimerism as a life-long physiological status in parous women: an immunological basis for its amplification in Scleroderma patients.

Arth. Rheum., 2003 Apr;48(4):1109-16.

Burastero SE, Galbiati S, Vassallo A, Sabbadini MG, Bellone M, Marchionni L, Smid M, Ferrero E, Ferrari A, Ferrari M, Cremonesi L.

Autoantibodies against a 72-kDa ductal cell membrane glycoprotein in a patient affected by syndrome and gastric MALT lymphoma.

Ann Hematol., 2002 Oct;81(10):597-602.

Folli F, Perego L, Ponzoni M, Girardi AM, Bosi E, Ferreri AJ, Bellone M, Sabbadini MG, Marchisio PC, Vicari AM, Trusolino L.

Cytotoxic and non-cytotoxic immunosuppressive agents. In: Immune-Mediated Disorders of the Central nervous System in children.

Lucia Angelini, Maria Bardare and Alberto Martini editors. John Libbey and Company Ltd, Eastleigh, England, 2002, pp. 245-260.

Sabbadini MG and Bellone M.

Takayasu’s arteritis. Therapeutic strategies.

J. Nephrol, 2001, 14(6):525-31.

Sabbadini MG, Bozzolo E, Baldissera E and Bellone M.

Remission from lupus nephritis resistant to cyclophosphamide after additional treatment with cyclosporin-A.

Rheumatology, 2000, 39:218-220.

Ferrario L, Bellone M, Baldissera E, Bozzolo E and Sabbadini MG.

Thymoma and systemic lupus erythematosus: an occasional association?

Lupus, 2000, 9:151-154.

Bozzolo E, Bellone M, Quaroni N, Voci C and Sabbadini MG.

Myasthenia Gravis: the immunobiology of an autoimmune disease.

Biology Intelligence Unit Series. R.G Landes Company, Austin, Texas. 1997.

Conti-Fine BM, Protti MP, Bellone M, Howard JF, Jr.

Impairment of lymphocyte suppressive system in recent onset insulin-dependent diabetes mellitus. Correlation with blood glucose and serum insulin levels.

Acta Diabetol Lat. 1989, 26:257-263.

Secchi A, Crosti F, Bonisolli L, Pavoni D, Capra F, Navone P, Pontiroli AE, Bellone M, Rugarli C and Pozza G.

Cimetidine treatment in hyper-IgM hypogammaglobulinemia.

JAMA-J Am Med Assoc. 1987, 258:1892.

Ciboddo G, Crosti F, Di Lucca G and Bellone M.

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